ASSOCIATION OF MARKERS OF THE SYSTEM OF FIBRINOLYSIS OF THE BLOOD PLASMA WITH А/С POLYMORPHISM OF DIOI AND PR0197LEU OF GPX1 GENES IN PATIENTS WITH NONVIRAL CHRONIC HEPATITIS AND LIVER CIRRHOSIS

Abstract

To study peculiarities of the indices of the fibrinolysis in patients with chronicdiffuse liver diseases depending A/C polymorphism in DI01 and GPX1 Pro197Leu gene. Extimation of the indices of fibrinolytic blood activity in patients with chronic diffuse liver disease showed that total fibrinolytic activity and enzymatic fibrinolytic activity were reliably lower than that of the control indices at the same time non-enzymatic fibrinolytic activity increased and did not reveal their dependence on the distribution of A/C polymorphism of DI01 gene and Pro197Leu polymorphism of GPX1.