Influence of Constant Lighting on Free Radical Oxidation of Biomolecules in Rats Exposed to Ethanol Intoxication

Abstract

Abstract. The aim of the research was to investigate the effects of constant lighting on oxidative stress biomarkers malonic aldehyde (MA) and oxidatively modified proteins (OMP) in blood and liver of rats exposed to alcohol intoxication. It was revealed that ethanol poisoning resulted in increase in MA and OMP, and liver was the most affected (by 90% and 42% higher than control). The increase in MA and OMP in the liver of rats exposed to combination of alcohol intoxication and constant light was more significant (by 139% and 88% above control respectively) than in alcohol treated animals kept under normal light conditions.