Acute kidney injury and ischemic stroke

Abstract

Patients with kidney dysfunction have an increased risk of renoparenchymal hypertension and cardiovascular complications (myocardial infarction, stroke, heart failure, cardiovascular death). In general, patients with kidney damage more often die not from end-stage renal failure, but from cardiovascular complications, in particular from stroke. The leading mechanisms for this include activation of the sympathetic and adrenal system, increased atherogenesis, endothelial dysfunction, increased inflammatory factors, changes in the level of lipoproteins, hypertrophy of the left ventricle, and the presence of hypertension.